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The DolPHIN 2 team

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Project Manager Helen leading a stakeholder mapping exercise

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Visiting the Gugulethu site, Cape Town

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Mother-to-child transmission of HIV is preventable, and we have a duty to ensure the burden of HIV is not handed down across generations.

Welcome to DolPHIN2

DolPHIN 2 is a multinational project led by the University of Liverpool which aims to reduce the rate of mother to child transmission (MTCT) of HIV through research into a new HIV drug called dolutegravir.

The project will investigate whether dolutegravir is superior to efavirenz-based regimens (the current standard of care within sub-Saharan Africa) at preventing mother to child transmission of HIV for women who begin HIV treatment in the third trimester of pregnancy. We aim to establish high-quality evidence and operational guidance for the use of dolutegravir (DTG) in late pregnancy through:

- A multi-site clinical trial – taking place in Uganda and South Africa

- Qualitative studies – assessing the acceptability of dolutegravir and the reasons for late presentation in pregnancy

- A Pharmacoeconomic study – assessing the cost effectiveness of dolutegravir against the standard of care in South Africa and Uganda.

Read more about DolPHIN 2 , find out about our team and access the latest resources on PMTCT and the project.

DolPHIN 2 is funded by UNITAID.


Twitter & News Feed

DolPHIN 2 Trial Manager and Trial Monitor to visit Cape Town site

The DolPHIN 2 trial opened for recruitment in our South African site last month. 

In light of this, the Trial Manager and

February 05, 2018 12:11

The External Monitor: The eyes and ears of the Sponsor!

Let me introduce myself first: I am Angela Colbers, working as a research assistant and post-doc at the Department of Pharmacy of the Radb...

January 25, 2018 14:25

The first participant has been recruited to the DolPHIN 2 trial!

On 22nd January 2018, our South African site opened to recruitment with the very first participant recruited into the DolPHIN-2...

January 25, 2018 12:37

The DolPHIN 2 Site Initiation Visits

On the 11th to 13th October 2017, we undertook the Site Initiation Visit (SIV) for the DolPHIN-2 study in Kampala, U...

November 29, 2017 16:08

The Liverpool team sets off for Uganda: IDI Site Initiation Visit

Today marks an important step in the set-up of the DolPHIN 2 trial, as key members of the Liverpool team make their way to Uganda for a Si...

October 09, 2017 13:51

DolPHIN-2 Consortium meeting, 27th -29th March 2017

After months of teleconferences, the  DolPHIN-2 project team finally came face to face at our first consortium meeting. 
At t...

May 03, 2017 13:34

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